Transcription factors GATA-4 and GATA-6 in normal and neoplastic human gastrointestinal mucosa

Abstract

The results suggest differential but overlapping functions for GATA-4 and GATA-6 in the normal gastrointestinal mucosa. Furthermore, GATA-4, GATA-6 and Ihh expression is altered in premalignant dysplastic lesions and reduced in overt cancer.