Bulky Chiral Carbene Ligands and Their Application in the Palladium‐Catalyzed Asymmetric Intramolecular α‐Arylation of Amides

Abstract

Bring on the big cats: New, C2-symmetric bulky N-heterocyclic carbene ligands bring major improvements in the palladium-catalyzed asymmetric intramolecular α-arylation of amides to give oxindoles (see picture, dba=trans,trans-dibenzylideneacetone), which are formed in high yield and excellent enantiomeric purity. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2007/z703408_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.