Polymorphism in the Microglial Cell-Mobilizing <i>CX3CR1</i> Gene Is Associated With Survival in Patients With Glioblastoma

Abstract

The common CX3CR1 allelic variant was associated with increased GBM survival and with reduced tumor infiltration by microglia. The CX3CR1 polymorphism does not seem to be a risk factor for GBM but may prove useful in predicting survival.