Cerebral Perfusion in Perinatal Hypoxia and Resuscitation Assessed by Transcranial Contrast-Enhanced Ultrasound and 3 T MRI in Newborn Pigs

Abstract

CEUS and DSC-MRI can detect an early temporal evolution of cerebral perfusion in perinatal hypoxia and resuscitation, reversible after 7 hours. Hyperoxic resuscitation caused early decreased cerebral perfusion, not present in the normoxic group. The combined use of CEUS and DSC-MRI can provide important diagnostic information and give new insights into perinatal vascular hypoxia mechanisms.