Cytokine‐induced prostaglandin E₂ production and cyclooxygenase‐2 expression in dental pulp cells: downstream calcium signalling via activation of prostaglandin EP receptor

Abstract

Interleukin-1beta and TNF-alpha may stimulate PGE(2) production in dental pulp cells. Activation of prostaglandin EP receptors in dental pulp cells by PGE(2) may induce Ca(2+) signalling to regulate cellular biological activity during inflammation.