Human Papillomavirus Infection in Oral Verrucous Carcinoma: Genotyping Analysis and Inverse Correlation with p53 Expression

Abstract

Thus, multiple infections with low- and high-risk HPVs and their rapid replication during hyperkeratinization may participate in the histogenesis of oral VC. Oral VC tumorigenesis may involve the inactivation of p53, which is associated with HPV infection.