A New Experimental Model of Polycystic Kidneys

Abstract

The production of polycystic renal disease in newborn rabbits by the use of a long-acting corticosteroid, fluprednisolone (Predef 2x [Greece]; Alphadrol; comparable US product) as reported by Perey et al has been confirmed and extended. Rabbits followed up to 3 months of age show disappearance of the cysts. Comparison with glomerular type human polycystic kidney shows important similarities.