Antibodies targeting p63 react specifically in the cytoplasm of breast epithelial cells exhibiting secretory differentiation

Abstract

Cells with secretory changes contain p63 protein or an antigenic equivalent. The detection of p63 protein continues to have considerable value for the identification of myoepithelial cells and thus the determination of invasion, but will also have value in the determination of secretory carcinomas of the breast and in understanding their development.