Tamoxifen Paradoxically Decreases Paclitaxel Deposition into Cerebrospinal Fluid of Brain Tumor Patients

Hepatogastroenterology

Yong Liu, Zong-Guang Zhou, Ke-Ling Chen et al. · Hepatogastroenterology · 2012 · 2.1K citations

Medicine, Molecular Biology, Oncology +17

Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites.

Carlos Cordon‐Cardo, James P. O’Brien, D Casals et al. · Proceedings of the National Academy of Sciences · 1989 · 1.7K citations · Full text

Medicine, Oncology, Pharmacology +16

Choroid plexus epithelial expression of <i>MDR</i> <i>1</i> P glycoprotein and multidrug resistance-associated protein contribute to the blood–cerebrospinal-fluid drug-permeability barrier

V. Venkat Rao, Julie L. Dahlheimer, Mark E. Bardgett et al. · Proceedings of the National Academy of Sciences · 1999 · 529 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

Alteration of etoposide pharmacokinetics and pharmacodynamics by cyclosporine in a phase I trial to modulate multidrug resistance.

B L Lum, Sonja Kaubisch, Alan M. Yahanda et al. · Journal of Clinical Oncology · 1992 · 301 citations

Pharmacy, Pharmacokinetics, Pharmacology +15

Changes in blood-brain barrier permeability induced by radiotherapy: Implications for timing of chemotherapy? (Review)

Marco van Vulpen, Henk B. Kal, Martin Taphoorn et al. · Oncology Reports · 2002 · 218 citations

Medicine, Oncology, Radiation Oncology +12