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Involvement of basic amino acid residues in transmembrane regions 6 and 7 in agonist and antagonist recognition of the human platelet P2Y12-receptor

ThrombopoiesisThrombosisPlatelet Aggregation InhibitorsSignal TransductionBiochemistryG Protein-coupled ReceptorMedicineBlood PlateletHuman Platelet P2y12-receptorAntagonist RecognitionReceptor (Biochemistry)PharmacotherapyPlatelet AntagonistPharmacologyTransmembrane Regions 6Drug Discovery