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Detection of glaucomatous retinal nerve fiber layer damage by scanning laser polarimetry with custom corneal compensation

DOI

28

Citations

0

References

2003

Year

Qienyuan Zhou, Jerry Reed, Ryan W. Betts, Peter K. Trost, Pak-Wai Lo, Charles Wallace, Richard H. Bienias, Guoqiang Li, Ross Winnick, William A. Papworth,
Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE

Abstract

One of the earliest signs of glaucoma presence is defects in the retinal nerve fiber layer (RNFL). Scanning laser polarimetry (SLP) provides objective assessment of RNFL, a birefringent tissue, by measuring the total retardation in the reflected light. SLP provides a potential tool for early detection of glaucoma and its progression. The birefringence of the anterior segment of the eye, mainly the cornea, is a confounding variable to SLP's clinical application, if compensation cannot be achieved properly. This paper presents a new SLP system, GDx VCC (Laser Diagnostic Technologies, Inc., San Diego, CA), with a variable corneal compensator (VCC) to achieve individualized corneal compensation. Clinical application of this device in glaucoma detection is also demonstrated.