BMJ · 1986 · 52 citations · 1 references
PharmacyPharmacologyDissolution TestingOsmolality AdjustmentPh DependencePh NeutralizationPh-osmolality Interactions
clotted within 30 minutes and had separated after overnight incubation.At pH 1 it solidified instantly, later to separate.In further testing to establish why this did not happen in vivo Osmolite-.asmixed with pepsin and adjusted to pH 1.The mixture became frothy, and solidification was considerably inhibited.A gastric aspirate from the patient was found to be pH 4.
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