Targeting X-Linked Inhibitor of Apoptosis Protein to Increase the Efficacy of Endoplasmic Reticulum Stress-Induced Apoptosis for Melanoma Therapy

Mutations of the BRAF gene in human cancer

Helen Davies, Graham R. Bignell, Charles Cox et al. · Nature · 2002 · 10.7K citations

Medicine, Genetics, Molecular Genetics +12

A System for Stable Expression of Short Interfering RNAs in Mammalian Cells

Thijn R. Brummelkamp, René Bernards, Reuven Agami · Science · 2002 · 4.3K citations · Full text

Life Sciences, Genetics, Molecular Biology +16

Prognostic Factors Analysis of 17,600 Melanoma Patients: Validation of the American Joint Committee on Cancer Melanoma Staging System

Charles M. Balch, Seng‐Jaw Soong, Jeffrey E. Gershenwald et al. · Journal of Clinical Oncology · 2001 · 2.4K citations

Medicine, Dermatology, Oncology +17

Downregulation of Bcl-2, FLIP or IAPs (XIAP and survivin) by siRNAs sensitizes resistant melanoma cells to Apo2L/TRAIL-induced apoptosis

Mamta Chawla‐Sarkar, Songa Bae, Frederic J. Reu et al. · Cell Death and Differentiation · 2004 · 359 citations

Life Sciences, Molecular Biology, Oncology +16

Antitumor effects of curcumin, alone or in combination with cisplatin or doxorubicin, on human hepatic cancer cells. Analysis of their possible relationship to changes in NF-kB activation levels and in IAP gene expression

Monica Notarbartolo, Paola Poma, Daniela Perri et al. · Cancer Letters · 2005 · 318 citations

Medicine, Oncology, Pharmacology +9