Concepedia

Is there a difference in the efficacy of peripartum antiretroviral regimens in reducing mother-to-child transmission of HIV in Africa?

Valériane Leroy, Charlotte Sakarovitch, Mario Cortina‐Borja, James McIntyre, Hoosen Coovadia, François Dabis, Marie‐Louise Newell

AIDS · 2005 · 85 citations · 16 references

DOI

Abstract

These results are in line with current World Health Organisation guidelines suggesting equivalence of choice between single-dose NVP and short-course ZDV, and confirm the greater efficacy of ZDV+3TC than with any single antiretroviral drug.

References

16

Prevention of Mother-to-Child HIV Transmission in Resource-Poor Countries

Kevin M. De Cock, Mary Glenn Fowler, Éric Mercier et al. · JAMA · 2000 · 1.1K citations

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Elective caesarean-section versus vaginal delivery in prevention of vertical HIV-1 transmission: a randomised clinical trial

The Lancet · 1999 · 585 citations

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Intrapartum and neonatal single-dose nevirapine compared with zidovudine for prevention of mother-to-child transmission of HIV-1 in Kampala, Uganda: 18-month follow-up of the HIVNET 012 randomised trial

J. Brooks Jackson, Philippa Musoke, Thomas R. Fleming et al. · The Lancet · 2003 · 523 citations

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6-month efficacy, tolerance, and acceptability of a short regimen of oral zidovudine to reduce vertical transmission of HIV in breastfed children in Côte d'Ivoire and Burkina Faso: a double-blind placebo-controlled multicentre trial

François Dabis, Philippe Msellati, Nicolas Méda et al. · The Lancet · 1999 · 506 citations

, , +7

Efficacy of three short-course regimens of zidovudine and lamivudine in preventing early and late transmission of HIV-1 from mother to child in Tanzania, South Africa, and Uganda (Petra study): a randomised, double-blind, placebo-controlled trial

The Lancet · 2002 · 462 citations

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