Analytical Chemistry · 2002 · 139 citations · 13 references
Natural SciencesChemistryAnalytical ChemistryInstrumentationMass Spectrometric AnalysisDetector SystemsMass AnalyzersMass MeasurementMass SpectrometryAmplificationHigh-resolution Mass AnalysisIon Trap Mass SpectrometryMass Spectrometry CharacterizationSample Introduction SystemsSpectrometer DesignTandem Mass SpectrometryTandem Mass Spectrometry Analysis
The authors describe a miniature cylindrical ion trap mass spectrometer and present preliminary performance data. The device is a battery‑operated cylindrical ion trap that preserves laboratory‑scale performance, supports tandem MS, and incorporates custom RF scanning, amplification, data acquisition, lens power supplies, software, and direct leak/membrane inlet systems. The instrument achieves a mass‑to‑charge range of about 250 Th with unit mass resolution.
A miniature cylindrical ion trap mass spectrometer is described, and preliminary data are presented. Functionality and performance of laboratory-scale instruments have been maintained to the extent possible in this battery-operated mass spectrometer. Capabilities include tandem mass spectrometry experiments. Custom-designed electronic components include the RF scanning and amplification system, data acquisition components, and lens power supplies, as well as a custom-software application. Direct leak and membrane introduction inlet systems are used for sample introduction. A mass/charge range of ∼250 Th with unit mass resolution has been demonstrated.
13