Cellular Basis for the Acute Inhibitory Effects of IL-6 and TNF- on Excitation-contraction Coupling

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

Grzegorz Grynkiewicz, Martin Poenie, Roger Y. Tsien · Journal of Biological Chemistry · 1985 · 21.7K citations · Full text

Natural Sciences, Biochemistry, Chemistry +17

Elevated Circulating Levels of Tumor Necrosis Factor in Severe Chronic Heart Failure

Beth Levine, Jill Kalman, Lloyd Mayer et al. · New England Journal of Medicine · 1990 · 2.6K citations · Full text

Medicine, Cardiology, Physiology +9

Negative Inotropic Effects of Cytokines on the Heart Mediated by Nitric Oxide

Mitchell S. Finkel, Carmine V. Oddis, Timothy D. Jacob et al. · Science · 1992 · 1.6K citations

Veterinary Medicine, Pharmacology, Physiology +14

Proinflammatory cytokine levels in patients with depressed left ventricular ejection fraction: A report from the studies of left ventricular dysfunction (SOLVD)

Guillermo Torre‐Amione, Samir Kapadia, Claude R. Benedict et al. · Journal of the American College of Cardiology · 1996 · 1.2K citations

Medicine, Cardiology, Internal Medicine +12

Increased plasma levels of interleukin-6 in sepsis [see comments]

C. Erik Hack, ER de Groot, RJ Felt-Bersma et al. · Blood · 1989 · 812 citations · Full text

Veterinary Medicine, Immunology, Pathology +12