Aberrant methylation of the specific CpG island portion regulates cyclooxygenase-2 gene expression in human gastric carcinomas

Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas

Charles E. Eberhart, R J Coffey, Radhika Aramandla et al. · Gastroenterology · 1994 · 2.5K citations · Full text

Medicine, Oncology, Pharmacology +16

Suppression of Intestinal Polyposis in ApcΔ716 Knockout Mice by Inhibition of Cyclooxygenase 2 (COX-2)

Masanobu Oshima, Joseph Dinchuk, Stacia Kargman et al. · Cell · 1996 · 2.4K citations · Full text

Life Sciences, Cell Biology, Molecular Genetics +16

Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2

Masahiko Tsujii, Raymond N. DuBois · Cell · 1995 · 2.3K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

A gene hypermethylation profile of human cancer.

Manel Esteller, Paul G. Corn, Stephen B. Baylin et al. · PubMed · 2001 · 2K citations

Medicine, Molecular Biology, Oncology +17

Alterations in DNA Methylation: A Fundamental Aspect of Neoplasia

Stephen B. Baylln, James G. Herman, Jeremy R. Graff et al. · Advances in cancer research · 1997 · 1.9K citations

Medicine, Genetics, Oncology +14