Mitochondrial dysfunction - the beginning of the end in Alzheimer's disease? Separate and synergistic modes of tau and amyloid-β toxicity

Triple-Transgenic Model of Alzheimer's Disease with Plaques and Tangles

Salvatore Oddo, Antonella Caccamo, Jason D. Shepherd et al. · Neuron · 2003 · 4.1K citations · Full text

Alzheimer's Disease, Dementia, Degenerative Disease +5

Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models

Lars M. Ittner, Yazi D. Ke, Fabien Delerue et al. · Cell · 2010 · 1.8K citations · Full text

Synaptic Plasticity, Neurodegenerative Diseases, Molecular Neuroscience +11

Formation of Neurofibrillary Tangles in P301L Tau Transgenic Mice Induced by Aβ42 Fibrils

Jürgen Götz, F. Chen, Jo Van Dorpe et al. · Science · 2001 · 1.5K citations

Abeta42 Injections, Molecular Biology, Synaptic Signaling +22

Mitochondrial Abnormalities in Alzheimer's Disease

Keisuke Hirai, Gjumrakch Aliev, Akihiko Nunomura et al. · Journal of Neuroscience · 2001 · 1.3K citations · Full text

Mitochondrial Abnormalities, Alzheimer's Disease, Mitochondrial Function +14

ABAD Directly Links Aß to Mitochondrial Toxicity in Alzheimer's Disease

Joyce W. Lustbader, Maurizio Cirilli, Chang Lin et al. · Science · 2004 · 1.3K citations

Mitochondrial Dysfunction, Molecular Biology, Cell Death +18