SECRETION OF TESTOSTERONE-ESTRADIOL-BINDING GLOBULIN BY A HUMAN HEPATOMA-DERIVED CELL LINE

Abstract

Using a sensitive radioimmunoassay for testosterone-estradiol-binding globulin (TeBG) we demonstrate that a human hepatoma-derived cell line secretes a protein which: (a) is immunologically indistinguishable from TeBG; (b) has the same Stokes radius as TeBG; (c) is absorbed by concanavalin A in the same way as TeBG in normal plasma.