Studies on antitumor mechanism of two planar platinum(II) complexes with 8-hydroxyquinoline: Synthesis, characterization, cytotoxicity, cell cycle and apoptosis

Platinum Compounds: a New Class of Potent Antitumour Agents

Barnett Rosenberg, Loretta Vancamp, James E. Trosko et al. · Nature · 1969 · 3.9K citations

Medicine, Medicinal Chemistry, Pharmacology +11

A Chemical Inhibitor of p53 That Protects Mice from the Side Effects of Cancer Therapy

Pavel G. Komarov, Elena A. Komarova, Roman V. Kondratov et al. · Science · 1999 · 1.3K citations

Medicine, Oncology, Pharmacology +17

Mechanism of ethidium bromide fluorescence enhancement on binding to nucleic acids

J. Olmsted, David R. Kearns · Biochemistry · 1977 · 563 citations

Natural Sciences, Biochemistry, Biophysics +11

A Novel Anticancer Gold(III) Dithiocarbamate Compound Inhibits the Activity of a Purified 20S Proteasome and 26S Proteasome in Human Breast Cancer Cell Cultures and Xenografts

Vesna Milacic, Di Chen, Luca Ronconi et al. · Cancer Research · 2006 · 319 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Quercetin-mediated cell cycle arrest and apoptosis involving activation of a caspase cascade through the mitochondrial pathway in human breast cancer MCF-7 cells

Chu-Chung Chou, Jai‐Sing Yang, Hsu-Feng Lu et al. · Archives of Pharmacal Research · 2010 · 317 citations

Life Sciences, Cell Biology, Oncology +17