Enduring Neurochemical Effects of Early Maternal Separation on Limbic Structures

Early, postnatal experience alters hypothalamic corticotropin-releasing factor (CRF) mRNA, median eminence CRF content and stress-induced release in adult rats

Paul M. Plotsky, Michael J. Meaney · Molecular Brain Research · 1993 · 1.6K citations

Life Sciences, Neurobiology, Neuroscience +13

Childhood abuse and neglect and loss of self-regulation.

Bessel A. van der Kolk, Rita E. Fisler · PubMed · 1994 · 362 citations

Social Sciences, Behavioral Sciences, Psychology +17

Endocrine responses to mother‐infant separation in developing rats

Cynthia M. Kuhn, John Pauk, Saul M. Schanberg · Developmental Psychobiology · 1990 · 242 citations

Life Sciences, Endocrinology, Physiology +17

Effects of early experience on adrenocortical reactivity

Robert Ader, Lee J. Grota · Physiology & Behavior · 1969 · 140 citations

Social Sciences, Physiology, Psychology +13

Relationship between Early Abuse, Posttraumatic Stress Disorder, and Activity Levels in Prepubertal Children

Carol A. Glod, Martin H. Teicher · Journal of the American Academy of Child & Adolescent Psychiatry · 1996 · 126 citations

Medicine, Pediatrics, Psychology +17