Analgesic and Toxic Effects of Neonicotinoid Insecticides in Mice

A subtype of nicotinic cholinergic receptor in rat brain is composed of alpha 4 and beta 2 subunits and is up-regulated by chronic nicotine treatment.

C M Flores, S W Rogers, L A Pabreza et al. · Molecular Pharmacology · 1992 · 875 citations

Life Sciences, Neuroscience, Pharmacology +17

Reduced antinociception in mice lacking neuronal nicotinic receptor subunits

Lisa M. Marubio, María del Mar Arroyo Jiménez, Matilde Cordero‐Erausquin et al. · Nature · 1999 · 547 citations

Life Sciences, Neurobiology, Neuroscience +12

Pentameric structure and subunit stoichiometry of a neuronal nicotinic acetylcholine receptor

Ellis Cooper, S. Couturier, Marc Ballivet · Nature · 1991 · 468 citations · Full text

Life Sciences, Biochemistry, Neuroscience +13

Nicotine-induced increase in neuronal nicotinic receptors results from a decrease in the rate of receptor turnover.

Xiaoyu Peng, Volodymyr Gerzanich, R Anand et al. · Molecular Pharmacology · 1994 · 390 citations

Life Sciences, Neuroscience, Pharmacology +11

Epibatidine, a potent analgetic and nicotinic agonist.

Barbara Badio, John W. Daly · Molecular Pharmacology · 1994 · 387 citations

Medicine, Medicinal Chemistry, Pharmacology +12