Inhibition of P-Glycoprotein Function by Several Antidepressants may not Contribute to Clinical Efficacy - Concepedia

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Inhibition of P-Glycoprotein Function by Several Antidepressants may not Contribute to Clinical Efficacy

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References

2005

Year

C. Weber, S. Kressmann, Mélanie Ott, Gert Fricker, Wernér E.G. Müller

Pharmacopsychiatry

Abstract

Because this inhibition is only seen at concentrations above therapeutically relevant plasma levels, their effect my not play a role for the mechanism of action of the antidepressants tested.