Gefitinib Radiosensitizes Stem-Like Glioma Cells: Inhibition of Epidermal Growth Factor Receptor-Akt-DNA-PK Signaling, Accompanied by Inhibition of DNA Double-Strand Break Repair

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

Shideng Bao, Qiulian Wu, Roger E. McLendon et al. · Nature · 2006 · 6.3K citations

Genome Instability, Radiation Therapy, Medicine +12

Isolation of cancer stem cells from adult glioblastoma multiforme

Xiangpeng Yuan, James F. Curtin, Yizhi Xiong et al. · Oncogene · 2004 · 789 citations

Neuro-oncology, Glioma, Medicine +8

NOTCH Pathway Blockade Depletes CD133-Positive Glioblastoma Cells and Inhibits Growth of Tumor Neurospheres and Xenografts  

Xing Fan, Leila Khaki, Thant S. Zhu et al. · Stem Cells · 2009 · 642 citations · Full text

Notch Blockade, Immunology, Cancer Biology +20

Cyclopamine-Mediated Hedgehog Pathway Inhibition Depletes Stem-Like Cancer Cells in Glioblastoma

Eli E. Bar, Aneeka Chaudhry, Alex Y. Lin et al. · Stem Cells · 2007 · 598 citations · Full text

Radiation-induced Epidermal Growth Factor Receptor Nuclear Import Is Linked to Activation of DNA-dependent Protein Kinase

Klaus Dittmann, Claus Mayer, Birgit Fehrenbacher et al. · Journal of Biological Chemistry · 2005 · 518 citations · Full text

Epidermal Growth Factor, Engineering, Radiation Effect +16