Validation of a Serologic Test for the Diagnosis of Helicobacter pylori Infection and the Immune Response to Urease and CagA in Children

Abstract

A serodiagnosis of H. pylori infection using native strains was developed. The difference in the immune response between children with RAP and control subjects suggests that RAP occurs during the acute phase of H. pylori infection. Our results also suggest that urease is a poor immunogen.