Endothelin increases cytoplasmic calcium and myosin phosphorylation in human myometrium

A novel potent vasoconstrictor peptide produced by vascular endothelial cells

Masashi Yanagisawa, Hiroki Kurihara, Sadao Kimura et al. · Nature · 1988 · 10.8K citations · Full text

Life Sciences, Cell Biology, Physiology +9

Calcium homeostasis in intact lymphocytes: cytoplasmic free calcium monitored with a new, intracellularly trapped fluorescent indicator.

Roger Y. Tsien, Tullio Pozzan, T J Rink · The Journal of Cell Biology · 1982 · 2.3K citations · Full text

Life Sciences, Biochemistry, Biophysics +13

Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endothelium-derived relaxing factor.

Gilberto De Nucci, Ranjeny Thomas, Pedro D’Orléans-Juste et al. · Proceedings of the National Academy of Sciences · 1988 · 1.4K citations · Full text

Medicine, Pharmacology, Physiology +12

Primary structure, synthesis, and biological activity of rat endothelin, an endothelium-derived vasoconstrictor peptide.

Masashi Yanagisawa, Akihiro Inoue, Tomohisa Ishikawa et al. · Proceedings of the National Academy of Sciences · 1988 · 547 citations · Full text

Medicine, Pharmacology, Physiology +13

Cellular mechanism of action by a novel vasoconstrictor endothelin in cultured rat vascular smooth muscle cells

Yoko Hirata, Hiroki Yoshimi, Satoru Takata et al. · Biochemical and Biophysical Research Communications · 1988 · 384 citations

Life Sciences, Cell Biology, Physiology +9