Screening and Diagnosis of Optic Pathway Gliomas in Children with Neurofibromatosis Type 1 by Using Sweep Visual Evoked Potentials

Abstract

Children with OPGs have reduced contrast sensitivity when assessed using the SVEP. Children with no OPGs display no differences in visual functioning compared with control subjects. The findings suggest that the SVEP can be a useful and noninvasive screening tool for early detection of visual pathway gliomas in children with NF-1 and normal visual acuity.