Concepedia

Improvement of functional recovery by chronic metformin treatment is associated with enhanced alternative activation of microglia/macrophages and increased angiogenesis and neurogenesis following experimental stroke

Qin Jin, Jian Cheng, Yang Liu, Jian Wu, Xiaoyu Wang, Shanwen Wei, Xiaomei Zhou, Zheng‐Hong Qin, Jia Jia, Xuechu Zhen

Brain Behavior and Immunity · 2014 · 295 citations · 29 references

DOI

Concepts

References

29

Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34)

The Lancet · 1998 · 8.3K citations

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Role of AMP-activated protein kinase in mechanism of metformin action

Gaochao Zhou, Robert P. Myers, Ying Li et al. · Journal of Clinical Investigation · 2001 · 5.4K citations

, , +16

Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group.

PubMed · 1998 · 4.3K citations

, , +17

Identification of Two Distinct Macrophage Subsets with Divergent Effects Causing either Neurotoxicity or Regeneration in the Injured Mouse Spinal Cord

Kristina A. Kigerl, John C. Gensel, Daniel P. Ankeny et al. · Journal of Neuroscience · 2009 · 2.2K citations · Full text

, , +17

Microglia/Macrophage Polarization Dynamics Reveal Novel Mechanism of Injury Expansion After Focal Cerebral Ischemia

Xiaoming Hu, Peiying Li, Yanling Guo et al. · Stroke · 2012 · 1.6K citations · Full text

, , +17