Adipose Tissue Gene Expression of Adiponectin, Tumor Necrosis Factor-.ALPHA. and Leptin in Metabolic Syndrome Patients with Coronary Artery Disease

Abstract

Our results demonstrate that TNF-α and leptin gene expressions increase prominently in the EAT, PAT and SAT while adiponectin gene expression decreases significantly in EAT and PAT in MS patients with CAD. These findings suggest that disturbances in expression of adiponectin, TNF-α and leptin in EAT, PAT and SAT might play an important role in MS patients with CAD.