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Induction of apoptosis in pediatric acute lymphoblastic leukemia (ALL) cells by the therapeutic opioid methadone and effective synergy with Bcl-2 inhibition

Hematological MalignancyMedicineMalignant Blood DisorderApoptosisPharmacologyEffective SynergyCell DeathPharmacotherapyOpioid OverdoseAnti-cancer AgentTherapeutic Opioid MethadoneOncologyDrug DiscoveryBcl-2 Inhibition