IL‐6 Modulates Hyperglycemia‐Induced Changes of Na+ Channel Beta‐3 Subunit Expression by Schwann Cells

Abstract

Our data show the suppressive effect of hyperglycemia on expression of voltage-gated Na+ channel beta3 subunit by Schwann cells as well as the protection of beta3 expression by treatment with IL-6. Our findings have direct relevance for therapy of diabetic neuropathy.