Modulation of Ca2+-Activated Cl− Secretion by Basolateral K+ Channels in Human Normal and Cystic Fibrosis Airway Epithelia

Increased Bioelectric Potential Difference across Respiratory Epithelia in Cystic Fibrosis

Michael R. Knowles, John T. Gatzy, Richard C. Boucher · New England Journal of Medicine · 1981 · 582 citations

Medicine, Pharmacology, Physiology +17

Altered Regulation of Airway Epithelial Cell Chloride Channels in Cystic Fibrosis

Raymond A. Frizzell, Gerhard Rechkemmer · Science · 1986 · 567 citations

Natural Sciences, Cell Biology, Physiology +17

Na+ transport in cystic fibrosis respiratory epithelia. Abnormal basal rate and response to adenylate cyclase activation.

Richard C. Boucher, M. Jackson Stutts, Michael R. Knowles et al. · Journal of Clinical Investigation · 1986 · 561 citations · Full text

Life Sciences, Cell Biology, Physiology +15

A constitutively open potassium channel formed by KCNQ1 and KCNE3

Björn C. Schroeder, Siegfried Waldegger, Susanne Fehr et al. · Nature · 2000 · 495 citations

Natural Sciences, Biochemistry, Biophysics +11

Activation by Extracellular Nucleotides of Chloride Secretion in the Airway Epithelia of Patients with Cystic Fibrosis

Michael R. Knowles, Lane L. Clarke, Richard C. Boucher · New England Journal of Medicine · 1991 · 494 citations · Full text

Medicine, Cell Biology, Pharmacology +17