BMJ Case Reports · 2012 · 10 citations · 8 references
MedicineOncologyOrthopaedic SurgeryBone MetabolismBone ScintigraphyOrthopaedic OncologyBone DisordersBone PathologyBone Tumor ImagingBone Tumor SurgeryBone TumorsSkeletal PathologyBone Tumor BiopsyBone Tumor HistopathologyMalignant Bone Tumor ImagingOsteolytic Bone LesionsOsteomalacia ImagingPathological Skeletal LesionsPositron Emission Tomography DetectionTumor-induced Osteomalacia
A 60-year-old man presented 2 years before his diagnosis with long-standing muscle cramping, progressive generalised weakness and chronic hip pain. The patient was found to have bilateral femoral neck pathologic fractures therefore, underwent reamed intramedullary nailing of both femurs. Laboratory studies showed hypophosphataemia. Bone marrow biopsy was negative for malignancy. Positron emission tomography demonstrated fludeoxyglucose uptake only in the posterior neck. Bone scan showed innumerable foci of increased activity throughout the skeleton consistent with pseudofractures seen in osteomalacia. Fine needle aspiration from the mass in the neck revealed a phosphaturic mesenchymal tumour of mixed connective tissue type. Resection of the mass in the neck resulted in resolution of generalised complaints with no evidence of recurrence with a follow-up of 12 months.
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Yehuda Handelsman, Jeffrey I. Mechanick, Lawrence Blonde et al. · Endocrine Practice · 2011 · 513 citations
Suzanne M. Jan de Beur · JAMA · 2005 · 251 citations
Medicine, Nephrology, Oncology +17
The Parathyroid Glands: What The Endocrine Surgeon Should Know
Nancy D. Perrier · Endocrine Practice · 2011 · 45 citations
Medicine, Endocrinology, Surgery +10