Cartilage Tissue Engineering in Plasma and Whole Blood Scaffolds

Abstract

Plasma and whole blood based scaffolds were used for cartilage tissue engineering. Chondrocytes were isolated, embedded into these structures, and cultivated for two weeks. To evaluate the neo-synthesized extracellular matrix quantitatively, the constructs were examined by classical techniques and NMR spectroscopy. Significant expression of characteristic extracellular matrix was found suggesting that these materials are well-suited grafts for artificial tissue. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2089/2008/adma200701344_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.