Studies on Coumarins of a Chinese Drug “Qian-Hu” V. Coumarin-glycosides from “Zi-Hua Qian-Hu”¹

Abstract

Decuroside V [3' ( R)-hydroxy-nodakenin-3'-ol] and decuroside IV [nodakenetin 4'- O-beta- D-apiofuranosyl (1-->6)beta-D-glucopyranolsyl], two new coumarin glycosides, were isolated from a Chinese drug sold under the name of Si-Qian-Hu (Seizenko) and Kwan-Si Qian-Hu (Koseizenko), the roots of PEUCEDANUM DECURSIVUM Maxim. (Umbelliferae). The structures were determined by means of spectroscopic analysis and chemical reactions. (1)H-NMR spectra showed the beta-configuration of the all sugar linkages.