Concepedia

Aberrations of MYC Are a Common Event in B-Cell Prolymphocytic Leukemia

Ellen Flatley, Andy I. Chen, Xiangrong Zhao, Elaine S. Jaffe, Jennifer Dunlap, Stefania Pittaluga, Shahed Abdullah, Susan B. Olson, Stephen E. Spurgeon, Guang Fan

American Journal of Clinical Pathology · 2014 · 42 citations · 16 references

DOIFull text

Open access

Abstract

These results suggest that deregulation of MYC plays an important role in the pathogenesis of B-PLL and expands the spectrum of B-cell neoplasms associated with aberrations of MYC.

References

16

Concurrent Expression of MYC and BCL2 in Diffuse Large B-Cell Lymphoma Treated With Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone

Nathalie A. Johnson, Graham W. Slack, Kerry J. Savage et al. · Journal of Clinical Oncology · 2012 · 954 citations

How I treat prolymphocytic leukemia

Claire Dearden · Blood · 2012 · 178 citations · Full text

<i>MYC</i> translocation and an increased copy number predict poor prognosis in adult diffuse large B‐cell lymphoma (DLBCL), especially in germinal centre‐like B cell (GCB) type

Sun Och Yoon, Yoon Kyung Jeon, Jin Ho Paik et al. · Histopathology · 2008 · 141 citations · Full text

p53 Abnormalities in B-Cell Prolymphocytic Leukemia

Daniela Lens, Pierre J. J. C. De Schouwer, Rifat Hamoudi et al. · Blood · 1997 · 123 citations · Full text

Increased MYC gene copy number correlates with increased mRNA levels in diffuse large B-cell lymphoma

C. J. Stasik, Hiroaki Nitta, Wenqing Zhang et al. · Haematologica · 2010 · 99 citations · Full text