Phosphorylation of Gi protein by cyclic AMP-dependent protein kinase inhibits its dissociation into α-subunits and βγ-subunits by Mg2+ and GTPγS

Protein kinase C phosphorylates the inhibitory guanine‐nucleotide‐binding regulatory component and apparently suppresses its function in hormonal inhibition of adenylate cyclase

Toshiaki Katada, Alfred G. Gilman, Yasuhiro Watanabe et al. · European Journal of Biochemistry · 1985 · 735 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

The regulatory component of adenylate cyclase. Purification and properties.

Paul C. Sternweis, John K. Northup, M D Smigel et al. · Journal of Biological Chemistry · 1981 · 504 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12

Two guanine nucleotide-binding proteins in rat brain serving as the specific substrate of islet-activating protein, pertussis toxin. Interaction of the alpha-subunits with beta gamma-subunits in development of their biological activities.

Toshiaki Katada, Masayuki Oinuma, M Ui · Journal of Biological Chemistry · 1986 · 315 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +8

Direct evidence for involvement of a guanine nucleotide-binding protein in chemotactic peptide-stimulated formation of inositol bisphosphate and trisphosphate in differentiated human leukemic (HL-60) cells. Reconstitution with Gi or Go of the plasma membranes ADP-ribosylated by pertussis toxin.

Akira Kikuchi, Osamu Kozawa, Kozo Kaibuchi et al. · Journal of Biological Chemistry · 1986 · 276 citations · Full text

Life Sciences, Biochemistry, Cell Biology +16

Effects of guanine nucleotides and Mg on human erythrocyte Ni and Ns, the regulatory components of adenylyl cyclase.

Juan Codina, John D. Hildebrandt, Lutz Birnbaumer et al. · Journal of Biological Chemistry · 1984 · 144 citations · Full text

Life Sciences, Biochemistry, Biology +13