Attenuated familial adenomatous polyposis due to a mutation in the 3′ part of the APC gene. A clue for understanding the function of the APC protein

Mutation and Cancer: Statistical Study of Retinoblastoma

Alfred G. Knudson · Proceedings of the National Academy of Sciences · 1971 · 7.6K citations · Full text

Life Sciences, Genetics, Oncology +16

Identification and characterization of the familial adenomatous polyposis coli gene

Joanna Groden, Andrew Thliveris, Wade S. Samowitz et al. · Cell · 1991 · 2.8K citations

Life Sciences, Genetics, Molecular Genetics +10

Identification of FAP Locus Genes from Chromosome 5q21

Kenneth W. Kinzler, Mef Nilbert, Li-Kuo Su et al. · Science · 1991 · 2.4K citations

Medicine, Genetics, Molecular Genetics +17

APC mutations occur early during colorectal tumorigenesis

Steven M. Powell, Nathan Zilz, Yasmin Beazer-Barclay et al. · Nature · 1992 · 1.9K citations

Medicine, Genetics, Molecular Genetics +14

Localization of the gene for familial adenomatous polyposis on chromosome 5

Walter F. Bodmer, Clyde Bailey, J. G. Bodmer et al. · Nature · 1987 · 1.4K citations

Life Sciences, Genetics, Molecular Genetics +11