The effect of combination antiretroviral therapy on CD5 B‐ cells, B‐cell activation and hypergammaglobulinaemia in HIV‐1‐infected patients

Abstract

Aviraemic HIV-infected patients on CART have lower plasma levels of IgG and IgA than viraemic HIV-infected patients, but levels are often above the normal range. CD5 B-cell numbers are depressed, so these cells are unlikely to contribute to hypergammaglobulinaemia in HIV-infected patients.