The relationship between the degree of neurodegeneration of rat brain 5-HT nerve terminals and the dose and frequency of administration of MDMA (`ecstasy')

Toxicity and deaths from 3,4-methylenedioxymethamphetamine ("ecstasy")

J.A. Henry, K.J. Jeffreys, S. Dawling · The Lancet · 1992 · 736 citations

Pharmacy, Pharmacology, Toxicology +10

3,4-Methylenedioxymethamphetamine and 3,4-methylenedioxyamphetamine destroy serotonin terminals in rat brain: quantification of neurodegeneration by measurement of [3H]paroxetine-labeled serotonin uptake sites.

Giuseppe Battaglia, S.Y. Yeh, Elizabeth O’Hearn et al. · Journal of Pharmacology and Experimental Therapeutics · 1987 · 459 citations

Medicine, Neuroscience, Pharmacology +16

Detection of Free Radical Activity During Transient Global Ischemia and Recirculation: Effects of Intraischemic Brain Temperature Modulation

Mordecai Y.‐T. Globus, Raul Busto, Baowan Lin et al. · Journal of Neurochemistry · 1995 · 389 citations

Medicine, Neuroscience, Pharmacology +15

The effects of 3,4-methylenedioxymethamphetamine (MDMA) and 3,4-methylenedioxyamphetamine (MDA) on monoaminergic systems in the rat brain

Donna M. Stone, Danese C. Stahl, Glen R. Hanson et al. · European Journal of Pharmacology · 1986 · 346 citations

Medicine, Neuroscience, Pharmacology +14

MDMA-induced neurotoxicity: Parameters of degeneration and recovery of brain serotonin neurons

George Battaglia, S.Y. Yeh, Errol B. De Souza · Pharmacology Biochemistry and Behavior · 1988 · 313 citations

Life Sciences, Neurobiology, Neuroscience +14