Diagnosis of canine exocrine pancreatic insufficiency by the assay of serum trypsin‐like immunoreactivity

Abstract

ABSTRACT A radioimmunoassay for canine serum trypsin‐like immunoreactivity (TLI) has been developed and evaluated for use in the diagnosis of exocrine pancreatic insufficiency (EPI). The maximum fasting TLI concentration in 14 dogs with EPI was 1.8 μg/l, compared with a minimum value of 7.0 μg/l in a control group of 75 dogs. The measurement of serum TLI therefore provides a sensitive test for the diagnosis of EPI in the dog.