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Effect of Bleeding on <i>in vivo</i> and <i>in vitro</i> Colony-Forming Hemopoietic Cells
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1977
Year
ImmunologyBlood CellPathologyColony-forming Hemopoietic CellsBone Marrow FailureHematologyBone MarrowStem CellsCell TransplantationSpleen Colony-forming UnitsHealth SciencesVascular BiologySustained IncreaseCell BiologyDevelopmental BiologyHemostasisStem Cell ResearchMedicineBlood Transfusion
The effect of bleeding on spleen colony-forming units (CFU-S) and on in vitro colony-forming cells with colony-stimulating factor (CFU-C) and erythropoietin (CFU-E) has been evaluated. The in vivo and in vitro colony-forming cells of the bone marrow show a decrease which for the CFU-E, CFU-C follows a short-lived increase. In the spleen, all progenitor cells assayed have shown a significant and sustained increase.