The Efficacy of Steroids in the Treatment of Idiopathic Sudden Hearing Loss: A Double-blind Clinical Study

TLDR

A double‑blind trial administered oral steroids to patients with idiopathic sudden hearing loss defined as ≥30‑dB loss across three contiguous frequencies within three days, using objective audiologic criteria and follow‑up audiograms at four weeks and three months. Steroids produced a statistically significant improvement in hearing recovery for patients with moderate losses, supporting the hypothesis that viral cochleitis underlies ISHL. Published in Arch Otolaryngol 106:772‑776, 1980.

Abstract

• Double-blind studies were conducted for the treatment of idiopathic sudden hearing loss (ISHL) with oral steroids. The condition was defined as not less than a 30-dB loss over three contiguous frequencies in three days or less. Follow-up audiograms were obtained four weeks and three months later. Specific audiologic guidelines for the assessment of hearing recovery were used to ensure objectivity. Steroids had a statistically significant effect on the recovery of hearing in patients with moderate hearing losses. The nature of the hearing loss and its susceptibility to improvement with steroid therapy lend support to the hypothesis that viral cochlitis is the primary cause of ISHL. (<i>Arch Otolaryngol</i>106:772-776, 1980)