Changes in Metabolic Profile and Adipoinsular Axis in Morbidly Obese Premenopausal Females Treated with Restrictive Bariatric Surgery

Abstract

The results of this study suggest that weight loss through restrictive bariatric surgery results in a significant reduction in leptin, resistin, and IL-6 levels, and an increase in adiponectin levels, in addition to improving insulin sensitivity and glucose and lipid homeostasis in young morbidly obese female patients. These changes were significantly correlated with the magnitude of weight loss.