Longitudinal quantification of inflammation in the murine dextran sodium sulfate-induced colitis model using μPET/CT1

Abstract

FDG-μPET-CT is a feasible and reliable noninvasive method to monitor murine DSS-induced colitis. The implementation of this technique in this widely used IBD model opens a new window for pathophysiological research and high-throughput screening of potential therapeutic compounds in preclinical IBD research.