THE PRESENCE OF A »GONADOTROPHIN INHIBITING SUBSTANCE« IN PINEAL GLAND EXTRACTS

Louis J. Soffer, Marvin Fogel, Amiel Z. Rudavsky

European Journal of Endocrinology · 1965 · 22 citations · 0 references

Concepts

Abstract

ABSTRACT A bovine pineal gland extract was found to inhibit the stimulatory effect of both human chorionic gonadotrophin (HCG) and human menopausal gonadotrophin (HMG) on mouse uterine weight, while melatonin displayed no such inhibitory activity. The pineal gland extract did not inhibit the stimulatory effect of oestrone.