Publication | Closed Access
Synthesis of Thiazolidine and Thiophene Derivatives for Evaluation as Anticancer Agents
42
Citations
18
References
2009
Year
Medicinal ChemistryPharmaceutical ChemistryHeterocyclicDerivative (Chemistry)MedicineChemical DerivativeOrganic ChemistryNovel ThiazolidinePharmacotherapyAnticancer AgentsAnti-cancer AgentHeterocycle ChemistryThiophene DerivativesPharmacologyRadiation OncologyEac CellsDrug Discovery
The non-isolated adducts (3a,b) were used as key intermediates to synthesize some novel thiazolidine and thiophene derivatives. Compound (4) exhibited a remarkable antitumor activity against EAC cells compared with the Doxorubicin as a positive control.
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