Relative risk for cancer in mucous membrane pemphigoid associated with antibodies to the β4 integrin subunit

Abstract

This incidence of cancer in MMP/OCP patients, with antibodies to human beta4 integrin subunit is considerably lower than expected. Preliminary observations in this and other studies suggest that serological subsets of MMP, based on antigen reactivity, have a different clinical course, prognosis and associations with cancer.