Concepedia

A general intramolecular Friedel–Crafts approach to functionalized pyrrolo[3,2,1-ij]quinolin-4-ones

Dadasaheb V. Patil, Marchello A. Cavitt, Paul Grzybowski, Stefan France

Chemical Communications · 2012 · 25 citations · 25 references

DOI

Concepts

Abstract

An indium(III)-catalyzed intramolecular Friedel-Crafts annulation for the efficient synthesis of pyrrolo[3,2,1-ij]quinolin-4-ones is described. The products are formed in good to excellent yields (51-97%) with diastereoselectivities up to >99 : 1 dr.

References

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