Concepedia

Synthetic retinoid CD437 induces mitochondria-mediated apoptosis in hepatocellular carcinoma cells

Kazue Gonda, Hiroyuki Tsuchiya, Tomohiko Sakabe, Yuji Akechi, Remina Ikeda, Ren Nishio, Kei Terabayashi, Kyoko Ishii, Yoshiaki Matsumi, An Afida Ashla,

Biochemical and Biophysical Research Communications · 2008 · 56 citations · 24 references

DOI

Concepts

References

24

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death

Zoltán N. Oltval, Curt Milliman, Stanley J. Korsmeyer · Cell · 1993 · 6K citations

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Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis

Atan Gross, Jennifer Jockel, Michael C. Wei et al. · The EMBO Journal · 1998 · 1.1K citations · Full text

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Prevention of Second Primary Tumors by an Acyclic Retinoid, Polyprenoic Acid, in Patients with Hepatocellular Carcinoma

Yasutoshi Muto, Hisataka Moriwaki, Mitsuo Ninomiya et al. · New England Journal of Medicine · 1996 · 674 citations · Full text

, , +17

Direct effect of Taxol on free radical formation and mitochondrial permeability transition

Gábor Várbiró, Balázs Veres, Ferenc Gallyas et al. · Free Radical Biology and Medicine · 2001 · 250 citations

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Induction of the Mitochondrial Permeability Transition Causes Release of the Apoptogenic Factor Cytochrome c

Joy C. Yang, Gino Cortopassi · Free Radical Biology and Medicine · 1998 · 215 citations

, , +13